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Mouse Indoleamine-2,3-Dioxygenase 2 (IDO2) ELISA Kit-Sandwich

Cat. No.EK6F426

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Indoleamine-2,3-Dioxygenase 2 (IDO2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse IDO2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Indoleamine-2,3-Dioxygenase 2 (IDO2).
Target Species Mouse
Species Reactivity Mouse
Detection Range 31.25-2000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Indoleamine 2,3-dioxygenase 2 (IDO2) catalyzes the initial and rate-limiting step in the kynurenine pathway of tryptophan catabolism, playing a role in immune regulation. In mice, IDO2's functions are primarily associated with immune regulation, inflammatory response, and autoimmune diseases. It influences immune cell function through both enzymatic and non-enzymatic mechanisms, contributing to pro-inflammatory effects under certain pathological conditions. IDO2 is crucial for the generation of T regulatory cells (Treg), a process dependent on the genetic function of IDO1. In IDO1-deficient mice, IDO2 function is impaired due to mismatched splicing of its expression.

Target/Biomarker Mouse IDO2
Target Synonym INDOL1; Indoleamine-Pyrrole 2;3 Dioxygenase-Like 1; Indoleamine 2;3-dioxygenase-like protein 1; Indoleamine-pyrrole 2;3-dioxygenase-like protein 1
Gene ID 209176
UniProt ID Q8R0V5

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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