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Mouse Glucose-6-Phosphatase, Catalytic (G6PC) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Glucose-6-Phosphatase, Catalytic (G6PC) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse G6PC in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The glucose-6-phosphatase catalytic subunit 1 is responsible for hydrolyzing glucose-6-phosphate to glucose within the endoplasmic reticulum. It collaborates with the glucose-6-phosphate transporter (SLC37A4/G6PT) to form the complex essential for glucose production in the final steps of glycogenolysis and gluconeogenesis, making it a critical enzyme for maintaining blood glucose homeostasis. G6PC knockout mice (e.g., G6pc−/−) exhibit severe hypoglycemia, accompanied by hepatic steatosis and cirrhosis. The function of G6PC is modulated by various metabolic signals, such as insulin and fructose intake, which influence its expression and activity.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.