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Mouse B- and T-lymphocyte attenuator (BTLA) ELISA Kit-Sandwich

Cat. No.EK5F54

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse B- and T-lymphocyte attenuator (BTLA) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse BTLA in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse B- and T-lymphocyte attenuator (BTLA).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.63-40 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

The B- and T-lymphocyte attenuator is an inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling through PTPN6/SHP-1 and PTPN11/SHP-2. It can interact either in cis (on the same cell) or in trans (on other cells) with TNFRSF14. In mice, this receptor is encoded by the BTLA gene. BTLA exhibits a wide range of immune regulatory functions in mouse models, involving a variety of pathological processes such as autoimmunity, infection, tumors and inflammation. Its potential as a therapeutic target is gradually being revealed, but its complex regulatory mechanism still needs further research.

Target/Biomarker Mouse BTLA
Target Synonym B and T lymphocyte associated protein; B and T lymphocyte attenuator; B and T lymphocyte associated; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; BTLA; BTLA1; CD272; CD272 antigen

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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