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Mouse Anti-Mouse Apolipoprotein B (APOB) Monoclonal Antibody
Product Overview
BioVenic mouse monoclonal antibody is specific for mouse apolipoprotein B. It is purified by protein A and protein G. It can be applied to WB, IHC, ICC and IP assays of mouse apolipoprotein B.
Specifications
Target Information
Mouse apolipoprotein B (ApoB) is a 512-kDa glycoprotein predominantly synthesized in mouse hepatocytes and intestinal enterocytes. It serves as the structural core of atherogenic lipoproteins (LDL, VLDL, chylomicrons), mediating lipid transport (cholesterol, triglycerides) throughout the murine circulatory system. Critical for systemic lipid homeostasis, it enables lipoprotein assembly and receptor-mediated uptake by peripheral tissues. Dysregulated expression or function associates with hypercholesterolemia, atherosclerosis, and fatty liver disease in mice. As a central mediator of lipid metabolism and a key marker of cardiovascular risk, mouse ApoB is a critical target for studying metabolic disorders, atherosclerotic pathobiology, and lipid-lowering therapeutic development.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.