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Rabbit Anti-Rat Von Hippel Lindau Tumor Suppressor (vHL) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat von hippel lindau tumor suppressor. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat von hippel lindau tumor suppressor.
Specifications
Target Information
Rat von Hippel-Lindau Tumor Suppressor (VHL) is an E3 ubiquitin ligase that targets hypoxia-inducible factor (HIF) for proteasomal degradation under normoxic conditions. It is widely expressed in kidney, liver, and brain, where it regulates oxygen sensing, angiogenesis, and energy metabolism. Loss of VHL function leads to accumulation of HIF and activation of hypoxic response genes, promoting tumorigenesis and vascular abnormalities. As a critical regulator of oxygen homeostasis, VHL is an important target for studies of hypoxia, cancer, and metabolic disorders.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.