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Rabbit Anti-Mouse Corin (CRN) Polyclonal Antibody

Cat. No.VD3N948

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse corin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse corin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C3N61
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Corin
Isotype IgG
Immunogen Recombinant protein of mouse corin
Purification Purified by Protein A
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse Corin is a cardiac type II transmembrane serine protease that activates atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) by cleaving their pro-forms in cardiomyocytes. Highly expressed in the heart and kidneys, Corin regulates blood pressure, natriuresis, and cardiac hypertrophy. Loss or mutation of Corin impairs peptide hormone activation, leading to hypertension and heart failure. As a key activator of the natriuretic peptide system, Corin is an important target for studies of cardiovascular homeostasis, hypertension, and cardiac remodeling.

Target Mouse Corin
Target Synonym ATC2; CRN; Lrp4; TMPRSS10; Atrial Natriuretic Peptide-Converting Enzyme, Serine Protease
Gene ID 53419
UniProt ID Q9Z319

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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