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Rabbit Anti-Mouse E1A Binding Protein P300 (EP300) Polyclonal Antibody

Cat. No.VD3N846

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse E1A binding protein p300. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse E1A binding protein p300.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N246
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse E1A Binding Protein P300
Isotype IgG
Immunogen Recombinant protein of mouse E1A binding protein p300
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse E1A binding protein p300 (EP300) is a 241-kDa nuclear acetyltransferase widely expressed in murine tissues, functioning as a key transcriptional co-activator. It regulates gene expression via histone acetylation and interactions with transcription factors (e.g., p53, NF-κB), modulating cellular processes including proliferation, differentiation, apoptosis, and DNA repair. Critical for mouse embryonic development, tissue homeostasis, and immune regulation, its dysregulation associates with developmental disorders, cancer, and inflammatory pathologies. As a master regulator of transcriptional networks and epigenetic modification, mouse EP300 is a critical target for studying gene regulatory mechanisms, oncogenesis, and epigenetically targeted therapeutics.

Target Mouse E1A Binding Protein P300
Target Synonym KAT3B; p300; Histone Acetyltransferase p300
Gene ID 328572
UniProt ID B2RWS6

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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