This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Utrophin (UTRN) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse utrophin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse utrophin.
Specifications
Target Information
Mouse Utrophin is a 395 kDa cytoskeletal protein that mirrors dystrophin's function, linking F-actin to the extracellular matrix via α-dystroglycan and β-dystroglycan. Expressed at neuromuscular and myotendinous junctions, it stabilizes the sarcolemma during contraction and clustering of acetylcholine receptors. In dystrophin-deficient muscle, utrophin is up-regulated and partially compensates for mechanical weakness. As a key regulator of membrane stability and a surrogate for dystrophin, utrophin is an important target for studies of muscular dystrophy, synapse formation, and therapeutic strategies aimed at enhancing its expression.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.