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Rabbit Anti-Mouse Neuronal Apoptosis Inhibitory Protein (NAIP) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse neuronal apoptosis inhibitory protein. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse neuronal apoptosis inhibitory protein.
Specifications
Target Information
Mouse neuronal apoptosis inhibitory protein (NAIP) is a 140 kDa cytosolic NLR whose three N-terminal baculoviral repeats grip activated caspases, while a C-terminal nucleotide-binding domain assembles inflammasome platforms. A solvent-exposed 18-aa "KVE" loop (aa 420-437) between BIR2 and BIR3 folds into a β-hairpin unique among mouse NLR proteins, presenting a conformational epitope preserved after aldehyde fixation. Affinity-purified antibodies targeting this loop trace native NAIP in spinal motor neurons, hippocampal pyramidal layers, and macrophage cytoplasm, delivering crisp punctate staining and single-band clarity on immunoblots with no cross-reaction to other IAP family members.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.