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Mouse Vinculin (VCL) ELISA Kit-Sandwich

Cat. No.EK5F532

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Vinculin (VCL) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse VCL in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Vinculin (VCL).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Vinculin is a protein that binds to actin filaments (F-actin) and is crucial for cell-matrix and cell-cell adhesion. It helps regulate the expression of E-cadherin on the cell surface and enhances the E-cadherin complex's ability to sense mechanical stimuli. Additionally, vinculin may significantly influence cell shape and movement. In mice, vinculin's primary functions include organizing the cytoskeleton, facilitating cell adhesion, and transmitting mechanical signals. Research using mouse models has demonstrated that vinculin is vital for early embryonic development, with its absence resulting in embryonic inviability.

Target/Biomarker Mouse VCL
Target Synonym MVCL; Metavinculin
Gene ID 22330
UniProt ID Q64727

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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