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Mouse Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Quiescin Q6 Sulfhydryl Oxidase 1 (QSOX1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse QSOX1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Sulfhydryl oxidase 1 facilitates the oxidation of sulfhydryl groups in peptide and protein thiols into disulfides while converting oxygen into hydrogen peroxide. This enzyme is crucial for forming disulfide bonds in a variety of extracellular proteins. QSOX1, a potent oxidase, primarily regulates mucin polymerization by catalyzing disulfide bond formation. In mice, a deficiency in QSOX1 results in compromised intestinal mucosal barrier function, characterized by decreased mucin secretion and disrupted intestinal flora balance. Notably, QSOX1-deficient mice are more susceptible to dextran sulfate (DSS)-induced colitis, exhibiting more severe symptoms such as shortened bowel and intensified colitis.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.