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Mouse Troponin I Type 2, Fast Skeletal (TNNI2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Troponin I Type 2, Fast Skeletal (TNNI2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TNNI2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Troponin I serves as the inhibitory subunit of the troponin complex, a thin filament regulatory component that imparts calcium sensitivity to the actomyosin ATPase activity in striated muscles. In mice, Tnni2 is involved in bone development, heart development, muscle contraction, and the progression of certain diseases. In DA2B mice, mutations in Tnni2 result in bone development disorders, linked to increased expression of the Hif3a gene. This suggests that Tnni2 plays a crucial role in regulating bone development and bone density.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Zhu, Xiaoquan et al. "A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice." PLoS genetics vol. 10,10 e1004589. 23 Oct. 2014.