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Bovine Alpha-Actinin-1 (ACTN1) ELISA Kit-Sandwich

Name: Bovine Alpha-Actinin-1 (ACTN1) ELISA Kit-Sandwich
SKU: EK11F729
Rating: 5 (1 reviews)

Cat. No.EK11F729

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Bovine Alpha-Actinin-1 (ACTN1) ELISA Kit-Sandwich is designed for the quantitative determination of Bovine Alpha-Actinin-1 (ACTN1) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Bovine ACTN1.

Target Species Bovine

Species Reactivity Bovine

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Alpha-Actinin-1 is a cross-linking protein that bundles actin filaments, essential for maintaining the cytoskeleton (cellular framework) and regulating cell shape, motility, and adhesion. It is encoded by the ACTN1 gene in cattle. It is highly expressed in hepatocellular carcinoma tissues and acts as a tumor promoter by suppressing Hippo signaling via physical interaction with MOB1. It may serve as a potential prognostic marker and therapeutic target for hepatocellular carcinoma.

Target/Biomarker Bovine ACTN1

Target Synonym actinin alpha 1; alpha-actinin-1; F-actin cross-linking protein; non-muscle alpha-actinin-1

Gene ID 524770

UniProt ID Q3B7N2

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Chen, Q. et al. ACTN1 supports tumor growth by inhibiting Hippo signaling in hepatocellular carcinoma. Journal of Experimental & Clinical Cancer Research. 2021, 40: 23.