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Porcine Granzyme M (GZMM) ELISA Kit-Sandwich

Cat. No.EK12F712

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Porcine Granzyme M (GZMM) ELISA Kit-Sandwich is designed for the quantitative determination of Porcine Granzyme M (GZMM) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Porcine GZMM.
Target Species Swine
Species Reactivity Swine
Detection Range 15.625-1000 pg/mL
Sensitivity 8.9 pg/mL
Recovery 80%-102%
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 270 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

Granzyme M (GzmM), also known as met-ase 1, is a serine protease expressed in various immune cells, including natural killer (NK) cells and activated lymphocytes. Granzymes are a group of neutral serine proteases stored in large cytoplasmic granules of immune cells. Granzyme M is encoded by the GZMM gene in pigs. It can degrade α-tubulin. GzmM may have a role in increasing local MIP-1α secretion during bacterial infection.

Target/Biomarker Porcine GZMM
Target Synonym granzyme M; granzyme M (lymphocyte met-ase 1)
Gene ID 100233186

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. de Jong, L. C. et al. Noncytotoxic functions of killer cell granzymes in viral infections. PLoS pathogens. 2021, 17: e1009818.
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