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Mouse Tripeptidyl Peptidase I (TPP1) ELISA Kit-Sandwich

Cat. No.EK6F362

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Tripeptidyl Peptidase I (TPP1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse TPP1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Tripeptidyl Peptidase I (TPP1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Tripeptidyl-peptidase 1 is a lysosomal serine protease known for its tripeptidyl-peptidase I activity. It likely functions as a non-specific lysosomal peptidase, producing tripeptides from breakdown products generated by lysosomal proteinases. In mice, the role of tripeptidyl-peptidase 1 (TPP1) is primarily linked to its degradation function in lysosomes, particularly in breaking down amyloid-β (Aβ) fibers. Mouse models show that TPP1 expression and activity differ across tissues, with notably high activity in the mouse brain, highlighting its significant role in brain function.

Target/Biomarker Mouse TPP1
Target Synonym CLN2; GIG1; LPIC; Tripeptidyl aminopeptidase; Lysosomal pepstatin-insensitive protease; Ceroid-Lipofuscinosis;Neuronal 2;Late Infantile; Cell growth-inhibiting gene 1 protein
Gene ID 12751
UniProt ID O89023

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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