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Mouse Pancreatic Polypeptide (PP) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Pancreatic Polypeptide (PP) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse PP in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Pancreatic polypeptide prohormone, secreted by pancreatic cells, regulates pancreatic and gastrointestinal functions, likely through the G protein-coupled receptor NPY4R2. Regarding bone microarchitecture and activity, PYY-deficient mice display enhanced osteoblast activity and increased trabecular bone volume. In contrast, PYY-overexpressing mice exhibit heightened bone resorption, indicated by an increased number of osteoclasts on the bone surface. Additionally, gender differences in bone metabolism were observed; PYY deficiency affects bone mass more significantly in female mice, whereas PYY overexpression has a more pronounced impact on male mice.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Wong, Iris P L et al. "Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biology." PloS one vol. 7,7 (2012): e40038.