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Mouse Secretory Leukocyte Peptidase Inhibitor (SLPI) ELISA Kit-Sandwich

Cat. No.EK5F625

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Secretory Leukocyte Peptidase Inhibitor (SLPI) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SLPI in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Secretory Leukocyte Peptidase Inhibitor (SLPI).
Target Species Mouse
Species Reactivity Mouse
Detection Range 15.7-1000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Antileukoproteinase is a proteinase inhibitor that remains stable in acidic conditions and binds strongly to enzymes such as trypsin, chymotrypsin, elastase, and cathepsin G. It plays a role in modulating the body's innate immune response following bacterial infections. This physiological inhibitor, known for inhibiting granulocytic serine proteases, is crucial in controlling inflammatory responses and preventing tissue damage. Research indicates that ALP serves to protect the mucosal barrier from excessive breakdown by proteolysis, inflammation, and microbial invasion by suppressing these proteases' activities. In mouse models, antileukocyte proteinase is linked to various diseases. For instance, in arthritis induced by anti-type II collagen antibodies, ALP diminishes joint inflammation by regulating neutrophil activity and preventing antibody-stimulated neutrophil adhesion to the synovial endothelium.

Target/Biomarker Mouse SLPI
Target Synonym ALK1; ALP; MPI; BLPI; HUSI; HUSI-I; WAP4; WFDC4; Antileukoproteinase; Seminal proteinase inhibitor; Mucus proteinase inhibitor; WAP four-disulfide core domain protein 4
Gene ID 20568
UniProt ID P97430

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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