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Mouse Melanoma Inhibitory Activity Protein 1 (MIA1) ELISA Kit-Sandwich

Cat. No.EK6F492

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Melanoma Inhibitory Activity Protein 1 (MIA1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MIA1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Melanoma Inhibitory Activity Protein 1 (MIA1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 78.25-5000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

The melanoma-derived growth regulatory protein has been found to inhibit the growth of melanoma cells in vitro, as well as other neuroectodermal tumors like gliomas. In mouse models, MIA exhibited significant inhibitory effects on melanoma cell growth by modulating the local microenvironment and impacting related signaling pathways. When melanoma cells overexpressing MIA were injected into mice, a marked reduction in tumor growth was observed, indicating that MIA continues to exert its tumor-inhibitory effects in a living organism. As a potential therapeutic target, MIA might inhibit melanoma growth and spread by blocking its secretion or function. Furthermore, studies have suggested that MIA may act synergistically with other tumor-related factors, such as MGSA/GRO, indicating that combined targeting of these factors could offer a more effective treatment strategy.

Target/Biomarker Mouse MIA1
Target Synonym CD-RAP; Melanoma-derived growth regulatory protein
Gene ID 12587
UniProt ID Q61865

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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