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Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a) ELISA Kit-Sandwich

Cat. No.EK6F527

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse HNF1a in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Hepatocyte Nuclear Factor 1 Alpha (HNF1a).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Hepatocyte nuclear factor 1-alpha (HNF1α) is a transcriptional activator that controls the tissue-specific expression of numerous genes, particularly in pancreatic islet cells and the liver. It activates the transcription of genes such as CYP1A2, CYP2E1, and CYP3A11. HNF1α has a wide range of crucial functions in mice, with its effects varying across tissues, including the pancreas, liver, kidney, and intestine. In the liver, HNF1α regulates the expression of various genes, including those involved in bile acid and cholesterol metabolism. Its absence can lead to disruptions in cholesterol metabolism, hepatocyte proliferation, and the development of conditions like fatty liver and liver cancer.

Target/Biomarker Mouse HNF1a
Target Synonym TCF1; HNF1; LFB1; LF-B1; MODY3; Transcription Factor 1;Hepatic; Hepatic Nuclear Factor; Albumin Proximal Factor; Liver-specific transcription factor LF-B1
Gene ID 21405
UniProt ID P22361

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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