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Mouse Mitochondrial Methionyl tRNA Formyltransferase (MTFMT) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Mitochondrial Methionyl tRNA Formyltransferase (MTFMT) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MTFMT in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Methionyl-tRNA formyltransferase, mitochondrial, is an enzyme that formylates methionyl-tRNA within mitochondria, playing a vital role in translation initiation. As a key enzyme in the mitochondrial translation process, Mtfmt is responsible for N-methylating the methionine residue on methionine-tRNA, thus facilitating the initiation and elongation of mitochondrial mRNA translation. Studies have shown that Mtfmt knockout mice experience significant metabolic disorders, including reduced glucose tolerance, decreased insulin sensitivity in adipose tissue, and improved liver metabolic health. Additionally, the absence of Mtfmt results in diminished mitochondrial activity and lowered oxidative phosphorylation levels, further impacting energy metabolism.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Sun, Xiaoxiao et al. "Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice." International journal of molecular sciences vol. 24,6 5999. 22 Mar. 2023.