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Mouse Heat Shock 27kDa Protein 1 (HSPB1) ELISA Kit-Sandwich

Name: Mouse Heat Shock 27kDa Protein 1 (HSPB1) ELISA Kit-Sandwich
SKU: EK5F357
Rating: 5 (1 reviews)

Cat. No.EK5F357

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Mouse Heat Shock 27kDa Protein 1 (HSPB1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse HSPB1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Mouse Heat Shock 27kDa Protein 1 (HSPB1).

Target Species Mouse

Species Reactivity Mouse

Detection Range 0.8-50 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%

Assay Time Around 90 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Heat shock protein beta-1 is a small heat shock protein that functions as a molecular chaperone, likely helping to keep denatured proteins in a folding-competent state. It contributes to stress resistance and the organization of actin. In mice, HSPB1 exhibits a wide range of biological functions, including neuroprotection, immunomodulation, inhibition of apoptosis, antioxidant effects, and protection against various pathological processes. HSPB1 demonstrates protective effects against neurodegenerative diseases in mouse models. For instance, in a mouse model of Niemann-Pick type C disease, overexpression of HSPB1 significantly reduced cell death and increased survival, underscoring its importance in neuronal cell protection.

Target/Biomarker Mouse HSPB1

Target Synonym HSP27; HSP-B1; CMT2F; HSP28; Hsp25; Heat Shock Protein 27; 28 kDa heat shock protein; Heat shock protein beta-1; Estrogen-regulated 24 kDa protein;

Gene ID 15507

UniProt ID P14602

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Chung, Chan et al. "Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease." PLoS genetics vol. 12,5 e1006042. 6 May. 2016.