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Mouse Succinate Dehydrogenase Complex Subunit A (SDHA) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Succinate Dehydrogenase Complex Subunit A (SDHA) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SDHA in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The succinate dehydrogenase [ubiquinone] flavoprotein subunit, located in the mitochondria, is a flavoprotein (FP) component of succinate dehydrogenase (SDH) within complex II of the mitochondrial electron transport chain. It plays a crucial role in transferring electrons from succinate to ubiquinone (coenzyme Q). In mice, knocking out the Sdha gene results in mild muscle fiber atrophy and mild behavioral or biochemical abnormalities. Sdha is also key in regulating cellular metabolic pathways. In a non-alcoholic fatty liver disease (NAFLD) model, the expression level of Sdha is closely linked to the liver's energy metabolism state. In addition, in the mouse brain, the activity and expression level of Sdha are generally higher in females than males.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Zaręba-Kozioł, Monika et al. "S-Palmitoylation of Synaptic Proteins as a Novel Mechanism Underlying Sex-Dependent Differences in Neuronal Plasticity." International journal of molecular sciences vol. 22,12 6253. 10 Jun. 2021.