This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Mouse Glyoxalase I (GLO1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Glyoxalase I (GLO1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse GLO1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Lactoylglutathione lyase, also known as Glo1, catalyzes the conversion of hemimercaptal, produced from methylglyoxal and glutathione, into S-lactoylglutathione. It plays a role in regulating TNF-induced transcriptional activity of NF-kappa-B and is essential for normal osteoclastogenesis. In mice, GLO1 serves various biological functions, including anti-oxidation, anti-glycosylation, metabolic regulation, tumor suppression, and neuroprotection. GLO1 is often overexpressed in many cancers and is associated with tumor progression. In a mouse fibrosarcoma model, GLO1 overexpression and its nuclear translocation are closely linked to tumor progression.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Bibars, Roaa S, and Qosay A Al-Balas. "Computational fragment-based drug design of potential Glo-I inhibitors." Journal of enzyme inhibition and medicinal chemistry vol. 39,1 (2024): 2301758.