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Mouse Angiogenin-4 (ANG4) ELISA Kit-Sandwich

Cat. No.EK6F910

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Angiogenin-4 (ANG4) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse ANG4 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Angiogenin-4 (ANG4).
Target Species Mouse
Species Reactivity Mouse
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Angiogenin-4 exhibits bactericidal properties against E. faecalis and L. monocytogenes, but not against L. innocua and E. coli. It promotes angiogenesis in vitro and shows low ribonuclease activity. Angiogenin-4 enhances melanoma cell proliferation without affecting endothelial or fibroblast cells in vitro. Beyond its antibacterial capabilities, Ang4 also plays a role in modulating intestinal microbiota composition. In mice, Ang4 expression is influenced by intestinal microbes, significantly increasing post-birth as microbial abundance rises. Additionally, cytokines like IL-25 and IL-13 regulate Ang4 expression.

Target/Biomarker Mouse ANG4
Target Synonym Angiogenin-4; Ang4; Angiogenin 4
Gene ID 219033
UniProt ID Q3TMQ6

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Noor, Zannatun et al. "Interleukin-25 Mediated Induction of Angiogenin-4 Is Interleukin-13 Dependent." PloS one vol. 11,4 e0153572. 18 Apr. 2016.
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