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Feline Chemokine C-X-C-Motif Receptor 4 (CXCR4) ELISA Kit-Sandwich

Cat. No.EK12F964

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Feline Chemokine C-X-C-Motif Receptor 4 (CXCR4) ELISA Kit-Sandwich is designed for the quantitative determination of Feline Chemokine C-X-C-Motif Receptor 4 (CXCR4) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Feline CXCR4.
Target Species Feline
Species Reactivity Feline
Detection Range 78.15-5000 pg/mL
Sensitivity 36.9 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%
Assay Time Around 210 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

CXCR4 is a receptor for stromal cell-derived factor-1 (SDF-1), which is a type of CXC chemokine that helps maintain the body's internal balance. Activation of CXCR4 in primary cultures of feline mammary carcinomas leads to an increase in the proliferative rate. The SDF-1/CXCR4 system appears to play a tumorigenic role in feline mammary gland malignancy, and in vitro cultures from these tumor samples may represent an experimental model to investigate the biological and pharmacological role of this chemokinergic axis.

Target/Biomarker Feline CXCR4
Target Synonym CD184; Fusin; NPYR; HSY3RR; LAP3; LCR1; LESTR; NPY3R; NPYRL; WHIM; Leukocyte-derived seven transmembrane domain receptor; Lipopolysaccharide-associated protein 3
Gene ID 493676
UniProt ID P56498

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

  1. Ferrari, A. et al. CXCR4 expression in feline mammary carcinoma cells: evidence of a proliferative role for the SDF-1/CXCR4 axis. BMC veterinary research .2012.8:27. 8, 27.
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