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Mouse Family With Sequence Similarity 135, Member B (FAM135B) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Family With Sequence Similarity 135, Member B (FAM135B) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse FAM135B in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
In mice, the FAM135B protein primarily functions in the DNA damage repair mechanism. It maintains the reserve of the Tip60-ATM complex by interacting with TIP60 and ATM proteins, thus promoting the DNA damage response (DDR). FAM135B enhances the cell's capability to repair DNA damage by supporting both homologous recombination (HR) and non-homologous end joining (NHEJ) repair pathways. For instance, mouse experiments have shown that overexpression of FAM135B significantly reduces the aggregation of γH2AX and 53BP1, highlighting its role in repairing double-strand breaks (DSBs).
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.