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Rabbit Collagen Type II (COL2) ELISA Kit-Sandwich

Cat. No.EK3F208

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Rabbit Collagen Type II (COL2) ELISA Kit-Sandwich is designed for the quantitative determination of Rabbit COL2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Rabbit COL2
Target Species Rabbit
Species Reactivity Rabbit
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Type II collagen serves as the foundation for hyaline cartilage, such as the articular cartilage found at joint surfaces. It is composed of homotrimers of collagen, type II, alpha 1 chains. Studies indicate that chondrocytes have the highest potential for synthesizing type II collagen in areas of moderately degenerated osteoarthritic articular cartilage. Collagen Type II is mainly involved in the functional maintenance of articular cartilage and intervertebral disc in rabbits. In articular cartilage, its expression is inhibited by certain compounds, which may lead to changes in cell function and morphology; whereas in the intervertebral disc, increased expression helps to promote the synthesis of the ECM, thereby enhancing cell function.

Target/Biomarker Rabbit COL2
Target Synonym Collagen Type II; COL2

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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