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Rabbit Anti-Rat Transketolase (TKT) Polyclonal Antibody

Cat. No.VD4N4

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat transketolase. It is purified by protein A. It can be applied to WB and IHC assays of rat transketolase.

Specifications

Application WB; IHC
Clonality Polyclonal
Classification Primary Antibody
Clone C3N76
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Transketolase
Isotype IgG
Immunogen Recombinant protein of rat transketolase
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat Transketolase is a thiamine-dependent cytosolic enzyme that catalyzes the reversible transfer of two-carbon ketol groups between sugar phosphates in the pentose phosphate pathway. It is highly expressed in liver, kidney, and brain, where it supplies NADPH for antioxidant defense and generates ribose-5-phosphate for nucleotide synthesis. Transketolase activity is sensitive to thiamine deficiency, leading to impaired energy metabolism and oxidative stress. As a key regulator of carbohydrate flux and cellular redox balance, transketolase is an important target for studies of metabolic disorders, thiamine metabolism, and cancer cell biology.

Target Rat Transketolase
Target Synonym TK; Wernicke-Korsakoff Syndrome
Gene ID 64524
UniProt ID P50137

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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