This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Rabbit Anti-Mouse Patched Homolog 1 (PTCH1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse patched homolog 1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse patched homolog 1.
Specifications
Target Information
Mouse Patched Homolog 1 (PTCH1) is a receptor involved in the Hedgehog signaling pathway, which plays a crucial role in embryonic development and tissue homeostasis. PTCH1 acts as a negative regulator of Hedgehog signaling by binding to Hedgehog ligands and inhibiting the activity of Smoothened (Smo). This interaction is essential for controlling cell proliferation, differentiation, and organogenesis. PTCH1 is expressed in various tissues and is critical for maintaining proper developmental processes and preventing abnormal cell growth. PTCH1 is an important target for studying Hedgehog signaling and related developmental disorders in mouse models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.