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Rabbit Anti-Mouse Chemokine (C motif) ligand (XCL1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse chemokine ligand. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse chemokine ligand.
Specifications
Target Information
Mouse chemokine ligand 1 (CCL1, TCA-3) is a 9 kDa secreted CC-chemokine whose N-terminal loop and 3₁₀ helix engage CCR8 on activated T-cells and macrophages, steering Th2 recruitment. A solvent-exposed 12-aa "SKP" surface (aa 30-41) between β2 and β3 strands folds into a β-hairpin unique among murine CCL proteins, presenting a conformational epitope preserved after glycosylation and fixation. Affinity-purified antibodies targeting this loop trace native CCL1 in thymic medulla, lung eosinophil foci, and mast-cell granules, delivering crisp extracellular deposition and single-band clarity on immunoblots with no cross-reaction to CCL2 or CCL3.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
