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Rabbit Anti-Mouse Chemokine (C motif) ligand (XCL1) Polyclonal Antibody

Cat. No.VD4N122

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse chemokine ligand. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse chemokine ligand.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C3N194
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Chemokine ligand
Isotype IgG
Immunogen Recombinant protein of mouse chemokine ligand
Purification Purified by Protein A
Concentration 1 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse chemokine ligand 1 (CCL1, TCA-3) is a 9 kDa secreted CC-chemokine whose N-terminal loop and 3₁₀ helix engage CCR8 on activated T-cells and macrophages, steering Th2 recruitment. A solvent-exposed 12-aa "SKP" surface (aa 30-41) between β2 and β3 strands folds into a β-hairpin unique among murine CCL proteins, presenting a conformational epitope preserved after glycosylation and fixation. Affinity-purified antibodies targeting this loop trace native CCL1 in thymic medulla, lung eosinophil foci, and mast-cell granules, delivering crisp extracellular deposition and single-band clarity on immunoblots with no cross-reaction to CCL2 or CCL3.

Target Mouse Chemokine ligand
Target Synonym Lptn; SCYC1; LTN; ATAC; SCM1-A
Gene ID 20290
UniProt ID P10146

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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