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Rabbit Anti-Mouse Chemokine (C-X-C Motif) Ligand 2 (CXCL2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse chemokine ligand 2. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse chemokine ligand 2.
Specifications
Target Information
Mouse Chemokine Ligand 2 (CCL2), also termed Monocyte Chemoattractant Protein-1, is a small secreted cytokine that guides Ly6C+ monocytes, memory T-cells and basophils to sites of injury or infection. Its N-terminal chemokine domain binds CCR2 with high specificity, triggering integrin activation and directional migration across vascular endothelium. Constitutively expressed by fibroblasts, endothelial and epithelial cells, CCL2 is rapidly up-regulated after cytokine or oxidative stress stimuli, serving as a reliable indicator of innate immune recruitment. Antibodies to mouse CCL2 enable precise quantification and localization of this key trafficking signal in inflammation, metabolic and neurodegenerative models.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.