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Rabbit Anti-Mouse Cytochrome P450 27B1 (CYP27B1) Polyclonal Antibody

Name: Rabbit Anti-Mouse Cytochrome P450 27B1 (CYP27B1) Polyclonal Antibody
SKU: VD3N899
Rating: 5 (1 reviews)

Cat. No.VD3N899

Product TypeVeterinary Antibodies

Size

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Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse cytochrome P450 27B1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse cytochrome P450 27B1.

Specifications

Application WB; IHC; ICC; IP

Clonality Polyclonal

Classification Primary Antibody

Clone C3N12

Host Rabbit

Target Species Mouse

Species Reactivity Mouse

Specificity Mouse Cytochrome P450 27B1

Isotype IgG

Immunogen Recombinant protein of mouse cytochrome P450 27B1

Purification Purified by Protein A

Concentration 0.5 mg/mL

Conjugation Unconjugated

Preservative and Stabilizer 0.02% Sodium Azide

Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol

Physical State Liquid

Target Information

Mouse Cytochrome P450 27B1 (CYP27B1) is a mitochondrial enzyme that catalyzes the 1α-hydroxylation of 25-hydroxyvitamin D to generate the active hormone calcitriol. Expressed predominantly in kidney, placenta, and immune tissues, it tightly controls calcium-phosphate homeostasis and bone mineralization. CYP27B1 activity is feedback-regulated by parathyroid hormone, calcitriol itself, and serum calcium levels. As the key activator of vitamin D signaling, CYP27B1 is an important target for studies of skeletal metabolism, immune modulation, and calcium-related disorders.

Target Mouse Cytochrome P450 27B1

Target Synonym VDD1, PDDR; CYP1, P450c1; 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase; Cytochrome P450 Family 27 Subfamily B Polypeptide 1; Calcidiol 1-monooxygenase

Gene ID 13115

UniProt ID O35084

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.