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Rabbit Anti-Mouse Angiopoietin Like Protein 3 (ANGPTL3) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse angiopoietin like protein 3. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse angiopoietin like protein 3.
Specifications
Target Information
Mouse angiopoietin-like protein 3 (ANGPTL3) is a 55-kDa secreted glycoprotein predominantly expressed in mouse hepatocytes, with low-level expression in adipose tissue and kidney. It belongs to the angiopoietin-like family, regulating lipid and glucose metabolism by inhibiting lipoprotein lipase (LPL) activity-reducing triglyceride clearance from plasma and modulating circulating lipid profiles. Beyond lipid regulation, it influences glucose homeostasis and hepatic lipid synthesis, linking metabolic pathways critical for murine energy balance. Dysregulated expression associates with hypertriglyceridemia, insulin resistance, and metabolic syndrome in mice. As a key mediator of systemic metabolic homeostasis, mouse ANGPTL3 is a critical target for studying metabolic disorders, lipid metabolism, and related cardiovascular pathologies.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.