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Rabbit Anti-Rat Glycoprotein A33 (GPA33) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat glycoprotein A33. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat glycoprotein A33.
Specifications
Target Information
Rat glycoprotein A33 (GpA33) is a 43-kDa trans-membrane mucin-type glycoprotein that belongs to the immunoglobulin superfamily. Restricted to the apical surface of intestinal epithelial cells, it acts as an intrinsic junctional stabilizer, maintaining monolayer integrity and regulating nutrient absorption. Its extracellular Ig-like domains mediate homophilic adhesion, while its short cytoplasmic tail links to PDZ scaffolds that modulate cytoskeletal dynamics. Expression is highest in the distal ileum and colon, making GpA33 a reliable marker of differentiated enterocytes. As a key guardian of gut barrier function and epithelial polarity, GpA33 is an important target for studies of inflammatory bowel disease, mucosal repair, and colorectal biology.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.