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Rabbit Anti-Rat Mucosae Associated Epithelia Chemokine (MEC) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat mucosae associated epithelia chemokine. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat mucosae associated epithelia chemokine.
Specifications
Target Information
Rat mucosae-associated epithelial chemokine (MEC/CCL28) is a 12 kDa secreted CC-chemokine whose C-terminal tail folds into a heparin-binding α-helix that tethers the peptide to mucosal surfaces, while the N-loop engages CCR10 and CCR3 for plasma-cell and eosinophil recruitment. A solvent-exposed "QEK" motif (aa 25-31) within the 30s helix is unique among rat chemokines, presenting a strain-specific epitope preserved after secretion and fixation. Polyclonal antibodies directed against this sequence detect native MEC in salivary glands, colon epithelium, and airway fluid, yielding crisp apical staining and single-band clarity on immunoblots with no cross-reaction to CCL27 or other CC-family ligands.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.