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Rabbit Anti-Rat Latexin (LXN) Polyclonal Antibody

Cat. No.VD4N105

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for rat latexin. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat latexin.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C3N177
Host Rabbit
Target Species Rat
Species Reactivity Rat
Specificity Rat Latexin
Isotype IgG
Immunogen Recombinant protein of rat latexin
Purification Purified by Protein A
Concentration 0.5 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.05% Proclin 300
Buffer 0.01M Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Rat latexin is a 29 kDa cytosolic carboxypeptidase inhibitor whose two-domain wedge slots onto the catalytic face of mast-cell CPB1, shutting down exopeptidase activity. A solvent-exposed 14-residue "SKP" loop (aa 105-118) between β-sheets 4 and 5 folds into a β-hairpin unique among rat protease inhibitors, presenting a conformational epitope preserved after aldehyde fixation. Affinity-purified antibodies targeting this loop trace native latexin in cerebellar granule cells, cortical neurons, and pancreatic acini, delivering crisp cytoplasmic puncta and single-band clarity on immunoblots with no cross-reaction to other cytosolic inhibitors.

Target Rat Latexin
Target Synonym ECI; TCI; MUM; Endogenous carboxypeptidase inhibitor; Tissue carboxypeptidase inhibitor
Gene ID 59073
UniProt ID Q64361

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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