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Rabbit Anti-Mouse Collagen Type I Alpha 2 (COL1a2) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse collagen type I alpha 2. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse collagen type I alpha 2.
Specifications
Target Information
Mouse collagen type I alpha 2 is a 140 kDa fibrillar chain whose Gly-X-Y repeats wind into heterotrimeric fibers, dominating bone, skin, and tendon extracellular matrix. A solvent-exposed 16-aa "KVE" loop (aa 235-250) within the triple helix folds into a β-turn unique among mouse fibrillar collagens, presenting a conformational epitope preserved after pepsin digestion and fixation. Affinity-purified antibodies targeting this loop trace native alpha 2 chains in calvarial bone, dermal stroma, and periodontal ligament, delivering crisp fibrillar tracks and single-band clarity on immunoblots with no cross-reaction to collagen type I alpha 1 or type III.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.