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Rabbit Anti-Mouse Tumor Protein P63 (TP63) Polyclonal Antibody

Cat. No.VD3N872

Product TypeVeterinary Antibodies

Size

Product Overview

BioVenic rabbit polyclonal antibody is specific for mouse tumor protein p63. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse tumor protein p63.

Specifications

Application WB; IHC; ICC; IP
Clonality Polyclonal
Classification Primary Antibody
Clone C2N272
Host Rabbit
Target Species Mouse
Species Reactivity Mouse
Specificity Mouse Tumor Protein P63
Isotype IgG
Immunogen Recombinant protein of mouse tumor protein p63
Purification Purified by Protein A
Concentration 0.89 mg/mL
Conjugation Unconjugated
Preservative and Stabilizer 0.02% Sodium Azide
Buffer Phosphate Buffered Saline, pH 7.4, with 50% glycerol
Physical State Liquid

Target Information

Mouse tumor protein p63 (TP63) is a 68-kDa transcription factor of the p53 family, predominantly expressed in murine epithelial stem/progenitor cells (skin, mammary gland, respiratory tract). It regulates gene networks controlling epithelial development, cell proliferation, differentiation, and apoptosis, while maintaining tissue homeostasis and regenerative capacity. Critical for murine embryonic morphogenesis (e.g., limb, craniofacial development) and epithelial barrier function, it acts as a tumor suppressor in certain tissues. Dysregulated isoform expression associates with epithelial dysplasia, carcinoma (e.g., squamous cell carcinoma), and developmental defects in mouse models. As a key mediator of epithelial biology and cancer progression, mouse TP63 is a critical target for studying epithelial pathobiology, tumorigenesis, and transcription factor-targeted therapeutics.

Target Mouse Tumor Protein P63
Target Synonym P63; TP73L; CUSP; EEC3; KET
Gene ID 22061
UniProt ID O88898

Shipping and Storage

This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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