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Rabbit Anti-Mouse Caspase 8 (CASP8) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for mouse caspase 8. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of mouse caspase 8.
Specifications
Target Information
Mouse caspase 8 (CASP8) is a 55-kDa cysteine protease and core mediator of extrinsic apoptosis. It localizes to the cytoplasm and is activated by death receptor signaling complexes, initiating a cascade of downstream caspase cleavage to drive programmed cell death. Expressed ubiquitously in mouse tissues-with notable levels in lymphoid organs, liver, and epithelial tissues-it also regulates immune signaling and inflammatory responses. Beyond apoptosis, it modulates cell survival and tissue homeostasis in physiological and pathological contexts. As a key regulator of cell death and immune pathways, mouse CASP8 is a critical target for studying apoptotic disorders, inflammatory diseases, and cancer-related mechanisms.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.