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Rabbit Anti-Rat Dopamine Receptor D1 (DRD1) Polyclonal Antibody
Product Overview
BioVenic rabbit polyclonal antibody is specific for rat dopamine receptor D1. It is purified by protein A. It can be applied to WB, IHC, ICC and IP assays of rat dopamine receptor D1.
Specifications
Target Information
Rat dopamine receptor D1 (DRD1) is a 49-kDa G protein-coupled receptor (GPCR) predominantly expressed in rat brain regions-including the striatum, prefrontal cortex, and nucleus accumbens. It binds dopamine to activate adenylyl cyclase, triggering cAMP-dependent signaling cascades that regulate neuronal excitability, synaptic plasticity, and neurotransmitter release. Beyond neural function, it modulates motor control, cognitive processes (learning, memory), reward pathways, and emotional regulation in rats. With limited expression in peripheral tissues, its brain-specific role is central to dopaminergic system homeostasis. As a key mediator of dopaminergic signaling, rat DRD1 is a critical target for studying neuropsychiatric disorders, movement disorders, and central nervous system (CNS) drug development.
Shipping and Storage
This product is shipped with wet ice packs. Store at -20°C on receipt (up to 12 months). Avoid repeated freezing and thawing as this may denature the antibody.
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.