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Mouse Von Willebrand Factor (vWF) ELISA Kit-Sandwich

Cat. No.EK5F2

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Von Willebrand Factor (vWF) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse vWF in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Von Willebrand Factor (vWF).
Target Species Mouse
Species Reactivity Mouse
Detection Range 1.25-80 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Von Willebrand factor plays a crucial role in maintaining hemostasis by facilitating the adhesion of platelets to sites of vascular injury. It does so by forming a molecular bridge between the sub-endothelial collagen matrix and the GPIb-IX-V receptor complex on platelet surfaces. Additionally, von Willebrand factor serves as a chaperone for coagulation factor VIII, ensuring its delivery to the injury site, stabilizing its heterodimeric structure, and protecting it from early clearance from the plasma. The most commonly utilized model for studying von Willebrand disease is the VWF-deficient mouse, which is created through homologous recombination.

Target/Biomarker Mouse vWF
Target Synonym F8VWF; VWD; von Willebrand antigen 2; vWF; Von Willebrand Factor
Gene ID 22371
UniProt ID Q8CIZ8

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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