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Mouse Stem Cell Factor Receptor (SCFR) ELISA Kit-Sandwich

Cat. No.EK5F461

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Stem Cell Factor Receptor (SCFR) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SCFR in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Stem Cell Factor Receptor (SCFR).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

The Stem Cell Factor Receptor, also known as the Mast/stem cell growth factor receptor Kit, is a tyrosine-protein kinase that serves as a cell-surface receptor for the cytokine KITLG/SCF. It plays a critical role in regulating cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, as well as melanogenesis. Upon binding with KITLG/SCF, the KIT receptor can activate multiple signaling pathways. The SCF/c-kit signaling pathway is vital for normal hematopoiesis. In mice, significant reductions in c-kit expression or impairment of SCF function lead to bone marrow hypoplasia, absence of mature mast cells, lack of pigmentation, and infertility.

Target/Biomarker Mouse SCFR
Target Synonym CD117; KIT; C-Kit; PBT; p145 c-Kit; C-Kit Receptor; Tyrosine-Protein Kinase; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Piebald Trait
Gene ID 16590
UniProt ID P05532

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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