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Mouse Myeloid Cell Leukemia Sequence 1, Bcl2 Related (MCL1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Myeloid Cell Leukemia Sequence 1, Bcl2 Related (MCL1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MCL1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
The induced myeloid leukemia cell differentiation protein Mcl-1 homolog plays a crucial role in regulating apoptosis versus cell survival and is essential for maintaining viability, though not proliferation. It exerts its effects by interacting with various other apoptosis regulators. Isoform 2 of this protein exhibits antiapoptotic activity. In acute myeloid leukemia (AML) mouse models, knocking out the MCL1 gene can lead to the death of tumor cells, significantly improving disease prognosis. Additionally, MCL1 is involved in c-Myc-driven leukemogenesis, indicating that MCL1 is central to the survival of leukemia cells.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.