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Porcine Low Affinity Immunoglobulin Gamma Fc Region Receptor III (FCGR3) ELISA Kit-Sandwich

Name: Porcine Low Affinity Immunoglobulin Gamma Fc Region Receptor III (FCGR3) ELISA Kit-Sandwich
SKU: EK12F571
Rating: 5 (1 reviews)

Cat. No.EK12F571

Product TypeAnimal Immunoassay Kits

Size

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Product Overview

BioVenic Porcine Low Affinity Immunoglobulin Gamma Fc Region Receptor III (FCGR3) ELISA Kit-Sandwich is designed for the quantitative determination of Porcine Low Affinity Immunoglobulin Gamma Fc Region Receptor III (FCGR3) in serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich

Specificity The assay kit is specific for Porcine FCGR3.

Target Species Swine

Species Reactivity Swine

Detection Range 0.625-40 ng/mL

Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 10%

Assay Time Around 270 min

Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell extract, and other biological fluids.

Target Information

FcgR3 is a cell surface receptor that binds to the Fc region of antibodies, triggering various immune responses, including phagocytosis (engulfment of pathogens) and antibody-dependent cellular cytotoxicity. It is one of the three classes of FcgRs. Antibody-dependent cellular cytotoxicity is initiated when the Fab and Fc portions of the mAb bind to both the tumor cell antigen and an activating FcgR, respectively, creating a bridge from the tumor cell to the effector cell.

Target/Biomarker Porcine FCGR3

Target Synonym Low affinity immunoglobulin gamma Fc region receptor III; IgG Fc receptor III; Cytolytic trigger molecule G7; Fc-gamma RIII; FcRIII; FCGR3; CD16

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

Datasheet

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

References

Mellor, J. D. et al. A critical review of the role of Fc gamma receptor polymorphisms in the response to monoclonal antibodies in cancer. Journal of Hematology & Oncology. 2013, 6: 1.