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Mouse Spondin 2 (SPON2) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Spondin 2 (SPON2) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SPON2 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Spondin-2 is a cell adhesion protein that facilitates the adhesion and outgrowth of embryonic hippocampal neurons. It directly binds to bacteria and their components, acting as an opsonin to enhance macrophage phagocytosis of bacteria, and also binds to bacterial lipopolysaccharide. Spondin-2 is crucial in initiating the innate immune response, serving as a distinctive pattern-recognition molecule in the extracellular matrix for microbial pathogens. In mouse models, a deficiency in SPON2 significantly hinders macrophage migration and function, indicating its vital role in immune regulation.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.
References
- Li, Nan et al. "Transcriptional Activation of Matricellular Protein Spondin2 (SPON2) by BRG1 in Vascular Endothelial Cells Promotes Macrophage Chemotaxis." Frontiers in cell and developmental biology vol. 8 794. 14 Aug. 2020.