Mouse Fibulin 3 (FBLN3) ELISA Kit-Sandwich

EGF-containing fibulin-like extracellular matrix protein 1 interacts with the EGF receptor (EGFR), stimulating EGFR autophosphorylation and triggering downstream signaling pathways. It may play a role in cell adhesion and migration and could function as a negative regulator of chondrocyte differentiation. Within the olfactory epithelium, it might regulate glial cell migration, differentiation, and their ability to support neuronal neurite outgrowth. EFEMP1 is crucial for forming elastic fibers in the extrahepatic bile ducts in mice. Research shows that mice deficient in EFEMP1 display reduced distribution and significantly fewer elastic fibers, leading to abnormal mechanical properties in the bile ducts, such as increased pressure compliance, resulting in a larger outer diameter and increased expansion capacity.