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Mouse Metallothionein 1 (MT1) ELISA Kit-Sandwich

Cat. No.EK5F435

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Metallothionein 1 (MT1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse MT1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Metallothionein 1 (MT1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 62.5-4000 pg/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Metallothioneins are characterized by a high cysteine content, which allows them to bind various heavy metals. These proteins are transcriptionally regulated by both heavy metals and glucocorticoids. In mice, MT-1 serves crucial biological functions, including providing antioxidant protection, regulating metal ion homeostasis, and defending against oxidative stress. Research has demonstrated that MT-1 is significantly expressed in mouse models of cerebral ischemia-reperfusion, with expression levels correlating with the protective effects observed after ischemia-reperfusion. Additionally, zinc can activate the transcription of the MT-1 gene by binding to the metal response element (MRE) in its promoter region.

Target/Biomarker Mouse MT1
Target Synonym MT1A; MT1S; MTC
Gene ID 17748
UniProt ID P02802

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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