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Mouse Checkpoint Kinase 1 (CHEK1) ELISA Kit-Sandwich

Cat. No.EK6F693

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Checkpoint Kinase 1 (CHEK1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CHEK1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Checkpoint Kinase 1 (CHEK1).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.17-10 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Serine/threonine-protein kinase Chk1 is an enzyme essential for checkpoint-mediated cell cycle arrest and the activation of DNA repair mechanisms in response to DNA damage or unreplicated DNA. CHEK1 is a critical part of mammalian cell cycle checkpoints, particularly in regulating the G2/M and S phase DNA damage checkpoints. In mouse embryos, the absence of CHEK1 results in severe cell cycle abnormalities, including spindle assembly checkpoint (SAC) dysfunction and impaired DNA damage repair. These issues cause embryonic development to arrest, ultimately leading to embryonic death.

Target/Biomarker Mouse CHEK1
Target Synonym CHK1; Cell cycle checkpoint kinase; Serine/threonine-protein kinase Chk1
Gene ID 12649
UniProt ID O35280

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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