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Mouse Checkpoint Kinase 1 (CHEK1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Checkpoint Kinase 1 (CHEK1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse CHEK1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Serine/threonine-protein kinase Chk1 is an enzyme essential for checkpoint-mediated cell cycle arrest and the activation of DNA repair mechanisms in response to DNA damage or unreplicated DNA. CHEK1 is a critical part of mammalian cell cycle checkpoints, particularly in regulating the G2/M and S phase DNA damage checkpoints. In mouse embryos, the absence of CHEK1 results in severe cell cycle abnormalities, including spindle assembly checkpoint (SAC) dysfunction and impaired DNA damage repair. These issues cause embryonic development to arrest, ultimately leading to embryonic death.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.