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Mouse Semaphorin 7A (SEMA7A) ELISA Kit-Sandwich

Cat. No.EK5F647

Product TypeAnimal Immunoassay Kits

Size

Product Overview

BioVenic Mouse Semaphorin 7A (SEMA7A) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SEMA7A in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.

Specifications

Assay Type ELISA-Sandwich
Specificity The assay kit is specific for Mouse Semaphorin 7A (SEMA7A).
Target Species Mouse
Species Reactivity Mouse
Detection Range 0.32-20 ng/mL
Reproducibility Intra-Assay: CV < 10%; Inter-Assay: CV < 12%
Assay Time Around 90 min
Sample Requirement Serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids.

Target Information

Semaphorin-7A is crucial for integrin-mediated signaling, playing a significant role in regulating cell migration and immune responses. It facilitates the formation of focal adhesion complexes, activates the protein kinase PTK2/FAK1, and leads to the subsequent phosphorylation of MAPK1 and MAPK3. Additionally, it enhances the production of pro-inflammatory cytokines by monocytes and macrophages, and is key in modulating inflammation and T-cell-mediated immune responses. In mice, Sema7A has a diverse range of functions, including immune regulation, inflammatory response, tumor progression, angiogenesis, neural regeneration, and defense against viral infections. It is particularly important in the mouse immune system for regulating the migration and function of immune cells. For instance, Sema7A promotes the migration and activation of monocytes by interacting with specific receptors such as Plexin C1 and β1 integrin, thus amplifying the inflammatory response.

Target/Biomarker Mouse SEMA7A
Target Synonym CD108; CDw108; H-SEMA-K1; H-Sema-L; JMH; SEMAK1; SEMAL; Semaphorin 7A;GPI Membrane Anchor; John Milton Hagen Blood Group; Semaphorin-K1; Semaphorin-L
Gene ID 20361
UniProt ID Q9QUR8

Shipping and Storage

This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).

Documents

COA

To request a Certificate of Analysis, please enter the Lot No. in the search box. Note: Certificate of Analysis not available for kits.

The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.

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