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Mouse Semaphorin 7A (SEMA7A) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Semaphorin 7A (SEMA7A) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse SEMA7A in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Semaphorin-7A is crucial for integrin-mediated signaling, playing a significant role in regulating cell migration and immune responses. It facilitates the formation of focal adhesion complexes, activates the protein kinase PTK2/FAK1, and leads to the subsequent phosphorylation of MAPK1 and MAPK3. Additionally, it enhances the production of pro-inflammatory cytokines by monocytes and macrophages, and is key in modulating inflammation and T-cell-mediated immune responses. In mice, Sema7A has a diverse range of functions, including immune regulation, inflammatory response, tumor progression, angiogenesis, neural regeneration, and defense against viral infections. It is particularly important in the mouse immune system for regulating the migration and function of immune cells. For instance, Sema7A promotes the migration and activation of monocytes by interacting with specific receptors such as Plexin C1 and β1 integrin, thus amplifying the inflammatory response.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.