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Mouse Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit-Sandwich
Product Overview
BioVenic Mouse Ryanodine Receptor 1, Skeletal (RYR1) ELISA Kit-Sandwich is designed for the quantitative determination of Mouse RYR1 in serum, plasma, tissue homogenate, cell culture supernatant, cell lysate, and other biological fluids using a Sandwich ELISA method. For research use only.
Specifications
Target Information
Ryanodine receptor 1 (RyR1) is a cytosolic calcium-activated channel responsible for mediating the release of Ca²⁺ from the sarcoplasmic reticulum (SR) into the cytosol, playing a crucial role in initiating muscle contraction after T-tubule depolarization. In mice, RyR1 is pivotal in regulating skeletal muscle excitation-contraction coupling and calcium ion signaling, with its dysfunction being linked to various diseases. RyR1 is essential in skeletal muscle, as it facilitates muscle contraction by releasing Ca²⁺ from the SR, which is central to the process of excitation-contraction coupling-where nerve signal activation results in Ca²⁺ release from the SR into the cytoplasm, thereby triggering muscle contraction.
Shipping and Storage
This product is shipped with gel ice packs. It is recommended to store at 2-8 °C (Up to 6 months).
Documents
The product is for research use only.
Not for commercial, prophylactic, diagnostic, or therapeutic applications.